Product Liability

Prempro Lawsuit

Prempro Lawsuit

Prempro Lawsuit

A Brief Guide to Filing a Prempro Lawsuit:

What is Prempro?

Prempro is a prescription medication that alleviates certain conditions and symptoms of menopause. Prempro is the brand name for an oral medication containing medroxyprogesterone acetate and estrogen. It is administered to women who experience severe menopause symptoms including dizziness or hot flashes. Prempro may also be administered to patients with vaginal atrophy and osteoporosis. Despite the drug’s effectiveness with regards to increasing estrogen levels, Prempro poses significant side effects.

Prempro Side Effects:

The most common Prempro side effects include back or abdominal pain; headaches; increased incidences of bacterial infections; pharyngitis; nausea; breast tenderness or pain; and itching. According to various studies conducted by the United States Food and Drug Administration, these Prempro side effects occur in roughly 10-30% of users.

Moreover, according to various reports issued by the Mayo Clinic, using prempro in conjunction with other medications such as isotretinoin (acne medication), felbamate, theophylline (lung disease medication) and.or paclitaxel (chemotherapy drug) increases the risk of Prempro side effects.

Similar to other estrogen supplements, Prempro increases the patient’s risk of developing blood clots, stroke, heart attacks, dementia and the development of estrogen-dependent tumors like endometrial or breast cancers. Additionally, Prempro side effects also include loss of vision, increased blood calcium levels and gallbladder disease.

Because of these side effects, Prempro is not safe for use during pregnancy. If a prospective user has a history of diabetes, epilepsy, asthma, heart problems, lupus, benign liver tumors, kidney disease, blood clots, gallstones, pancreatitis, or vision loss, it is not safe to consume Prempro.

Prempro FDA:

In January of 2003, the FDA and Wyeth (Prempro’s manufacturer) revised the prescribing information to include boxed warnings to aptly reflect that estrogens and estrogens combined with progestin therapies should not be applied for the prevention of cardiovascular disease. This FDA warning includes risk information from the Women’s Health Initiative study, which reported increased risks of stroke, myocardial infarction, pulmonary emboil, invasive breast cancer and deep vein thrombosis in postmenopausal women during a 5-year conjugated equine estrogen treatment plan. Because of these Prempro side effects, estrogens should be prescribed at the lowest effective dosage levels and for the shortest duration possible.

Prempro Lawsuits:

Due to the aforementioned side effects, Pfizer—the drug’s manufacturer—has faced a whirlwind of Prempro lawsuits. The bulk of these Prempro lawsuits allege that use of the drug caused breast cancer.
To elaborate, the Women's Health Initiative in 2002, released a report stating that Prempro side effects included an increased risk of heart attacks, strokes, clots and breast cancer. These disclosures both decreased drug sales and increased the number of women seeking a Prempro lawsuit.

Prempro lawsuits stem from the drug’s chemical makeup; Prempro combines Premarin with progestin—a combination that results in an increased risk of breast cancer. A swarm of Prempro lawsuits were filed in response to the Women’s Health Initiative Report. The number of plaintiffs seeking Prempro lawsuits escalated at roughly 10,000. A large percentage of these Prempro lawsuits; however, were dismissed before reaching formal trial.

The first noteworthy Prempro lawsuit took place in April 2006. Prior to this period, no Prempro lawsuit had come to trial. Although this Prempro lawsuit was ultimately dismissed, the second litigation effort resulted in a $1.5 million settlement for a woman whose Prempro side effects included the development of breast cancer. The number of Prempro lawsuits exponentially grew in the subsequent years, as more and more users were developing breast cancer.


In 2007, a $134.1 million Prempro settlement was awarded to three Nevada women who developed breast cancer. In 2009, in response to similar Prempro lawsuits, the FDA added a warning to elaborate the risks associated with breast cancer.

In 2011, it was reported that the first large-scale Prempro lawsuit was disbursed by Pfizer. Reports stated that roughly 2,200 Prempro lawsuits resulted in a Prempro settlement for the plaintiff. By 2012, it was reported that the company had paid $896 million as remuneration in Prempro lawsuits.

At this time, Pfizer estimates that it has resolved two-thirds of its Prempro lawsuits. It is not known how many cases were dropped before trial or how many plaintiffs received out-of-court compensation; however, a 2009 study published in The Lancet indicated that Prempro side effects might include the development of lung cancer. If further studies determine that this is the case, it is possible that more people will pursue a Prempro lawsuit.

Initially, many cases seeking compensation for Prempro side effects were handled in in an Arkansas federal court as part of consolidated multidistrict litigation.
 

Sources:

1. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm153358.html

2. http://www.fda.gov/Safety/MedWatch/SafetyInformation/Safety-RelatedDrugLabelingChanges/ucm116295.html

Share

Related Articles

Product Liability News

Veggie Patch Recalls Meatless Burger and Falafel On November 30, 2012, the Food and Drug Administration (FDA) announced that VEGGIE PATCH® is voluntarily recalling two products because of a risk of Listeria monocytogenes contamination.
Sportspower Recalls Waterslides for Children Sportspower Recalls Waterslides for Children On November 28, 2012, the Consumer Product Safety Commission (CPSC) announced that Sportspower Ltd based out of Hong Kong has recalled children’s waterslides because of an injury hazard.
Sportspower Recalls Trampolines Because of Injury Hazard Sportspower Recalls Trampolines Because of Injury Hazard On November 28, 2012, the Consumer Product Safety Commission (CPSC) announced the Sportspower Ltd is voluntarily recalling a model of trampolines because of serious injury risks.
Kirkland Sauté Pans and Glass Lids Recalled Kirkland Sauté Pans and Glass Lids Recalled On November 28, 2012, the Consumer Product Safety Commission (CPSC) reported that Kirkland Signature Six-Quart Pans and glass lids were voluntarily recalled for a laceration hazard.
Toro Riding Mowers Recalled for Fire Hazard Toro Riding Mowers Recalled for Fire Hazard On November 27, 2012, the Consumer Product Safety Commission announced that The Toro Co issued a voluntary recall of several models of the Toro® Z Master® Riding Mower.
Step2 Recalls Children’s Riding Toy for Fall Hazard Step2 Recalls Children’s Riding Toy for Fall Hazard On November 27, 2012, the Consumer Product Safety Commission (CPSC) reported that the Step2 Company LLC in Streetsboro, Ohio was issuing a voluntary recall for a children’s riding toy because of a fall hazard.
Capital City Fruit Issues Recall of Cherry Tomatoes Capital City Fruit Issues Recall of Cherry Tomatoes On November 21, 2012, the Food and Drug Administration (FDA) announced that Capital City Fruit, Inc from Norwalk, Iowa is voluntarily recalling cherry tomatoes that were shipped to Rio Queen Citrus Inc on November 10, 2012.
Carolina Prime Pet Inc Recalls All Natural Bullstrips Carolina Prime Pet Inc Recalls All Natural Bullstrips On November 20, 2012, the Food and Drug Administration (FDA) announced that Carolina Prime Pet Inc was recalling its Priority Total Pet Care All Natural Bullstrips that come in a package of five.
Hunter Douglas Recalls Window Coverings Hunter Douglas Recalls Window Coverings On November 21, 2012, the Consumer Product Safety Commission (CPSC) announced that Hunter Douglas Fabrication Co issued recalls to repair custom cellular and pleated window coverings.
Kid’s Pajamas Recalled for Violating Flammability Standards Kid’s Pajamas Recalled for Violating Flammability Standards On November 20, 2012, the Consumer Product Safety Commission (CPSC) announced that J.
Kenny’s Farmhouse Cheese Announces Voluntary Recall Kenny’s Farmhouse Cheese Announces Voluntary Recall As of November 5, 2012, the Food and Drug Administration announced that Kenny’s Farmhouse Cheese was issuing a voluntary recall for certain cheese products because several test samples tested positive for Listeria monocytogenes.
Mindray DS USA Recalls A3/A5 Anesthesia Delivery System Mindray DS USA Recalls A3/A5 Anesthesia Delivery System On November 14, 2012, the Food and Drug Administration (FDA) announced a recall that could affect a huge percentage of the medical industry.
New Federal Safety Standards for Infant Swings New Federal Safety Standards for Infant Swings On November 13, 2012, the Consumer Product Safety Commission (CPSC) voted and approved new federal safety standards for infant swings.
Powermate Generators Recalled for Fire Hazard Powermate Generators Recalled for Fire Hazard On November 13, 2012, the Consumer Product Safety Commission (CPSC) announced a recall that could potentially affect consumers currently using generators for power after Hurricane Sandy.
Nielsen-Kellerman Microphones Recalled for Shock Risk Nielsen-Kellerman Microphones Recalled for Shock Risk On November 13, 2012, the Consumer Product Safety Commission (CPSC) announced that Nielson-Kellerman Co is voluntarily recalling a type of microphone because the product can shock and burn the face.
Columbus Camping Chairs Recalled for Mold Presence Columbus Camping Chairs Recalled for Mold Presence On November 13, 2012, the Consumer Product Safety Commission (UPSC) announced that Basin and Columbus™ are voluntarily recalling certain folding camping chairs because the chairs may contain certain kinds of mold that can cause health problems.
Three Britax Child Restraint Models Recalled Three Britax Child Restraint Models Recalled On November 12, 2012, the National Highway Traffic Safety Administration announced that three different models of Britax child restraints were being recalled because of a choking hazard.
Jimmy Dean® Recalls Sandwich for Undeclared Allergens Jimmy Dean® Recalls Sandwich for Undeclared Allergens On November 10, 2012, the Food and Drug Administration (FDA) announced the Jimmy Dean® was voluntarily recalling its Jimmy Dean French Toast & Sausage Sandwich with the following code: 12292P1.
Diamondback Bicycles Issues Recall for Crash Hazard Diamondback Bicycles Issues Recall for Crash Hazard On November 8, 2012, the Consumer Product Safety Commission announced that certain Diamondback bicycles were being recalled because parts of the bicycle can fail and cause the rider to crash at significant speeds.
Nestlé USA Recalls Nesquik® Chocolate Powder Nestlé USA Recalls Nesquik® Chocolate Powder On November 8, 2012, the Food and Drug Administration announced that Nestlé USA was recalling Nesquik® Chocolate Powder that comes in 10.
Monessen Hearth Systems Recalls Fireplaces and Inserts Monessen Hearth Systems Recalls Fireplaces and Inserts On November 8, 2012, the Consumer Product Safety Commission announced that Monessen Hearth Systems Co issued a recall for numerous gas fireplaces and inserts.
LG Recalls Electric Ranges after Burn and Fire Hazard LG Recalls Electric Ranges after Burn and Fire Hazard On November 8, 2012, the Consumer Product Safety Commission announced that LG Electronics is recalling several models of electric ranges because they pose a burn and fire hazard.
Multiple Scuba Hoses Recalled after Drowning Hazard Multiple Scuba Hoses Recalled after Drowning Hazard On November 7, 2012, the Consumer Product Safety Commission stated that Innovative Scuba Concepts, Trident Diving, and A-Plus Marine are recalling certain models of scuba diving hoses because they can burst.
Huge Recall Issued for ZuPreem Bird Foods Huge Recall Issued for ZuPreem Bird Foods Premium Nutritional Products, Inc has recently announced a voluntary recall of their ZuPreem FruitBlend™ With Natural Fruit Flavors bird foods that are used for large and medium/large birds.
Master Forge Gas Grills Recalled for Fire and Burn Hazard Master Forge Gas Grills Recalled for Fire and Burn Hazard On November 6, 2012, the Consumer Product Safety Commission (CPSC) announced that a particular model of Master Forge Gas Grills is being voluntarily recalled.
Select Evenflo Big Kid Booster Seats Recalled Select Evenflo Big Kid Booster Seats Recalled On October 22, 2012, the Department of Transportation announced that certain Evenflo Big Kid Factory Select booster seats do not meet requirements under No.
Banana Boat Sun Care Products Withdrawn Nationwide Banana Boat Sun Care Products Withdrawn Nationwide On October 19, 2012, the Food and Drug Administration announced that Energizer Holdings Inc issued a voluntary market withdrawal for continuous spray Banana Boat products.
Huge Recall of Manual Resuscitators by Ventlab Corp Huge Recall of Manual Resuscitators by Ventlab Corp On October 16, 2012, the Food and Drug Administration announced that Ventlab Corporation issued a recall across the nation for a total of 14,602 manual resuscitators.
Infant Swing Recalled for Strangulation Hazard Infant Swing Recalled for Strangulation Hazard On October 18, 2012, the Consumer Product Safety Commission (CPSC) announced that Dream On Me Inc based out of South Plainfield, New Jersey, is voluntarily recalling their Happy Swing II infant swings.
Trend Lab Issues Recall for Children’s Upholstered Chairs Trend Lab Issues Recall for Children’s Upholstered Chairs On October 18, 2012, the Consumer Product Safety Commission (CPSC) announced the voluntary recall by Trend Lab LLC in Burnsville, Minnesota for their children’s upholstered toddler chairs.

Guide To: Product Liability Lawyers

Guide to Finding Defective Product Lawyer How do I find a Defective Product Lawyer?A defective product lawyer represents people who have been injured by an item during their everyday use.